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Catalog Number: (76285-070)
Supplier: Enzo Life Sciences
Description: Recombinant monclonal antibody (Human IgG3κ).

Recommended Applications: ELISA, WB


Catalog Number: (76284-870)
Supplier: Enzo Life Sciences
Description: Recombinant monclonal antibody (Mouse IgG2bλ).

Recommended Applications: Flow Cytometry, WB


Catalog Number: (76284-628)
Supplier: Enzo Life Sciences
Description: Recombinant monclonal antibody (Human IgG1κ).

Recommended Applications: ELISA, Flow Cytometry, IF, WB


Catalog Number: (10050-156)
Supplier: Enzo Life Sciences
Description: The cell division cycle (cdc) group of proteins consists of many protein classes, including cyclin dependent kinases (Cdks), phosphoprotein phosphatases, mitogen activated kinases, small GTPases, and cyclins. These proteins play a central role in regulating progression through the cell cycle through the formation and/or modification of key substrates. Cdc42 belongs to the Rho-family of GTPases, and promotes actin polymerization to form filopodia. Cdc25A is a dual-specificity phosphatase that acts on phosphorylated threonine and tyrosine residues of Cdks, leading to binding and activation of their partner cyclins.


Catalog Number: (10051-966)
Supplier: Enzo Life Sciences
Description: Bax is an appromimately 22 kDa pro-apoptotic protein belonging to the Bcl-2 family of proteins, which are characterized by the presence of at least one Bcl-2 homology (BH) domains. Bax normally resides in the cytoplasm, but following an apoptotic stimuli, Bax undergoes a conformational change and translocates to mitochondrial membranes where it inserts and mediates the release of cytochrome c. This activates caspase-3 and perpetuates the apoptotic cascade.


Catalog Number: (10050-118)
Supplier: Enzo Life Sciences
Description: p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to Mdm2, SV40 T antigen and human Papilloma virus E6 protein. p53 senses DNA damage and facilitates its repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovary, bladder, colon, lung, and melanoma.


Catalog Number: (10049-822)
Supplier: Enzo Life Sciences
Description: The RICK (Receptor-interacting serine/threonine protein kinase 2) protein, also known as RIP-like interacting CLARP kinase, and CARD-containing ICE associated kinase, contains an N-terminal kinase domain and a C-terminal CARD domain. Overexpression of RICK results in the activation of NF-κB pathway and also induces apoptosis. RICK represents a kinase that regulates TNF and Fas induced-apoptosis and that is involved in the generation of proinflammatory cytokine IL-1beta.


Catalog Number: (95040-504)
Supplier: Enzo Life Sciences
Description: The Hsp70 family of heat shock protiens contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78). Hsp70 family members contain highly conserved N-terminal ATP-ase and C-terminal protein binding domains. Binding of peptide to Hsp70 is assisted by Hsp40, and stimulates the inherent ATPase activity of Hsp70, facilitating ATP hydrolysis and enhanced peptide binding. Hsp70 nucleotide exchange and substrate binding coordinates the folding of newly synthesized proteins, the re-folding of misfolded or denatured proteins, coordinates trafficking of proteins across cellular membranes, inhibits protein aggregation, and targets the degradation of proteins via the proteasomal pathway.


Supplier: Enzo Life Sciences
Description: Isotype matched controls are useful in flow cytometry to determine a gross estimate of non-specific binding that may be observed with a specific antibody of interest. In general, an isotype control should be of the same species and isotype as the antibody of interest, used at the same concentration, and conjugated to the same fluorophore. This reagent is an IgG1 isotype mouse monoclonal antibody (Clone # MOPC-21) conjugated to phycoerythrin (PE). It is intended for use as an isotype control antibody for flow cytometry.

Supplier: Enzo Life Sciences
Description: Selective inhibitor of JAK1 and JAK2 kinases including the JAK2 V617F mutant

Supplier: Enzo Life Sciences
Description: Wnt pathway activator

Supplier: Enzo Life Sciences
Description: Palbociclib, also known as PD0332991, is an orally available pyridopyrimidine-derived cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity.

Supplier: Enzo Life Sciences
Description: Bax is an appromimately 22 kDa pro-apoptotic protein belonging to the Bcl-2 family of proteins, which are characterized by the presence of at least one Bcl-2 homology (BH) domains. Bax normally resides in the cytoplasm, but following an apoptotic stimuli, Bax undergoes a conformational change and translocates to mitochondrial membranes where it inserts and mediates the release of cytochrome c. This activates caspase-3 and perpetuates the apoptotic cascade.

Catalog Number: (76201-750)
Supplier: Enzo Life Sciences
Description: Recommended Applications: ELISA, Flow Cytometry, WB

Species reactivity: Human


Catalog Number: (10136-008)
Supplier: Enzo Life Sciences
Description: Detect 5-hydroxymethylcytosine using a robust glucosylation method

SDS


Catalog Number: (76002-574)
Supplier: Enzo Life Sciences
Description: Recommended Applications: ELISA, IP, WB, ChIP

Species reactivity: Human, Saccharomyces cerevisiae


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
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