QS11 ≥98% (by HPLC)

Supplier: SAFE AND SURE NEDERLAND B.V.
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BML-WN117-0005 BML-WN117-0025
76002-256EA 191 USD
76002-256 76002-258
QS11 ≥98% (by HPLC)
QS11

Wnt pathway activator


Synergizers with Wnt3a to activate the Wnt/β-catenin pathway. Binds and inhibits GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1), thus activating ARF. It has also been suggested that a possible mechanism by which QS11 synergizes Wnt is through ARFGAP1 inhibition leading to increased β-catenin translocation via ARF activation.

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