XAV939 ≥98% (by TLC)

Supplier: SAFE AND SURE NEDERLAND B.V.
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Total Ratings: 0
Avg. Ratings: 0.0 out of 5

BML-WN100-0005 BML-WN100-0025
76002-190EA 80.66 USD
76002-190 76002-192
XAV939 ≥98% (by TLC)
XAV939

PARP5a inhibitor


Potent inhibitor of Tankyrase 1 (IC50=11nM) and Tankyrase 2 (IC50=4nM). Inhibition of tankyrase promotes stabilization of axin resulting in β-catenin degradation and Wnt signalling disruption. Inhibits proliferation of the μ-catenin-dependent colon carcinoma cell line DLD-1. Promotes cardiomyogenic development in mesoderm progenitor cells.

Formula: C₁₄H₁₁F₃N₂OS
MDL Number: MFCD16879017
CAS Number: 284028-89-3

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