BI-D1870 ≥98% (by HPLC)

Supplier: SAFE AND SURE NEDERLAND B.V.
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BML-EI407-0001 BML-EI407-0005
76002-100EA 98.1 USD
76002-100 76002-102
BI-D1870 ≥98% (by HPLC)
BI-D1870

S6 kinase inhibitor


Cell permeable, ATP-competitive inhibitor of the four isoforms of ribosomal S6 kinase (p90 RSK) (IC50's at 100µM ATP: RSK1 = 31nM, RSK2 = 24nM, RSK3 = 18nM, RSK4 = 15nM). Does not significantly inhibit 10 other AGC kinases, and over 40 other protein kinases at 100X concentrations. Acts on the N-terminal AGC kinase domain. Completely prevents PMA-induced TSC2 phosphorylation.

Formula: C₁₉H₂₃F₂N₅O₂
MDL Number: MFCD11223662
CAS Number: 501437-28-1

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