Flumequine (synthetic) ≥97% (by HPLC)

Supplier: Van Der Voort Lucht en Milieu Amste

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CDX-F0079-G005 CDX-F0079-G025

102989-990EA 123.23 USD

102989-990 102989-992

Flumequine (synthetic) ≥97% (by HPLC)

Flumequine

Flumequine is a fluoroquinolone synthetic chemotherapeutic antibiotic used to treat bacterial infections.

Inhibits topoisomerases
Used to study hepatocarcinogenicity
Targets primarily gram-negative bacteria

Targets primarily gram negative bacteria, especially those which cause enteric infections in animals. It is used to study processes that affect mammalian chromosome and DNA unwinding at the level of gyrase/topoisomerases. It inhibits topoisomerases, which are needed for the transcription and replication of bacterial DNA. The inhibition of the topoisomerases results in strand breakage of the bacterial chromosome, supercoiling and resealing. Therefore, DNA replication and transcription is inhibited. It was also used to study hepatocarcinogenicity and DNA damage in mice and the mechanisms of quinolone resistance.

White to off-white powder

Soluble in toluene

Formula: C₁₄H₁₂FNO₃
Storage Temperature: Freezer

MDL Number: MFCD00079298
CAS Number: 42835-25-6

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