Forskolin ≥98% (by HPLC, TLC)
Supplier: Van Der Voort Lucht en Milieu AmsteTotal Ratings: 0
Avg. Ratings: 0.0 out of 5
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Warning
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Potent, cell permeable adenylyl cyclase activator. Increases intracellular cAMP levels. Widely used tool to investigate cAMP as a second messenger. Inotropic and antihypertensive. Smooth muscle relaxant/vasodilator. Glucose transporter inhibitor. Platelet aggregation inhibitor. Stimulates lipolysis in fat cells. Non-competitive nicotinic acetylcholine receptors inhibitor. MAP kinase inhibitor. Upregulates mitochondrial uncoupling protein (UCP) mRNA levels in brown adipose tissue. Autophagy inhibitor. Hedgehog signaling inhibitor. Has antiglaucoma potential. Promotes neuronal differentiation of NSCs.
Formula:
C₂₂H₃₄O₇ Storage Temperature: Freezer |
MDL Number:
MFCD00082317 CAS Number: 66575-29-9 |
Specification Test Results
Source/Host | Isolated from Coleus forskohlii. |
Purity |
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Appearance/Color | White to off-white solid. |
Solubility | Soluble in ethyl acetate, anhydrous DMSO or ethanol; very poorly soluble in water. DMSO is the recommended solvent for activation of cAMP. |
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