Baricitinib phosphate salt ≥95%

Supplier: Van Der Voort Lucht en Milieu Amste

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102992-154EA 246.46 USD

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Baricitinib phosphate salt ≥95%

Baricitinib phosphate salt

Baricitinib is a selective JAK1 and JAK2 inhibitor. IC(50) values are 5.9nm for JAK1, and 5.7nM for JAK2. In cell based assays Baricitinib/INCB-28050 demonstrated inhibition of intracellular signaling of multiple pro-inflammatory cytokines including IL-6 and IL-23 at concentrations of 50nM, and also showed good efficacy in a number of animal models at doses of 10mg/kg and below. Baricitinib is in Phase III development as a potential treatment for rheumatoid arthritis. It is in Phase II development as a potential treatment for psoriasis and diabetic nephropathy

Formula: C₁₆H₁₇N₇O₂S·H₃PO₄
MW: 469.4 g/mol
Storage Temperature: Freezer

MDL Number: MFCD25976707
CAS Number: 1187595-84-1

Specification Test Results

Purity	95%
Appearance/Color	Solid.
Solubility	Soluble in DMSO or ethanol.

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