CC-401 hydrochloride ≥95%

Supplier: Van Der Voort Lucht en Milieu Amste
Ratings: (No Reviews)

Total Ratings: 0
Avg. Ratings: 0.0 out of 5

SYN-1028-M001 SYN-1028-M005 SYN-1028-M010 SYN-1028-M050
102991-462EA 171.69 USD
102991-462 102991-464 102991-466 102991-468
CC-401 hydrochloride ≥95%
CC-401 hydrochloride

CC-401 is a competitive inhibitor of the ATP binding site in the active, phosphorylated, form of JNK. This prevents JNK from phosphorylating its various target molecules, including the amino terminus of c-Jun. It is a potent inhibitor of all three forms of JNK (Ki of 25-50 nM), and has at least 40-fold selectivity for JNK compared with other related kinases, including: p38, ERK, IKK2, PKC, Lck, and ZAP70. CC-401 acts to inhibit JNK signaling by competitive binding to the adenosine triphosphate-binding site in the active, phosphorylated, form of JNK, resulting in inhibition of the phosphorylation of JNK targets, such as the amino-terminal activation domain of the transcription factor, c-Jun. In cell-based assays, 1-5 muM CC-401 provides specific JNK inhibition.

Formula: C₂₂H₂₄N₆O·HCl
MW: 424.9 g/mol
Storage Temperature: Freezer
MDL Number: MFCD21364765
CAS Number: 1438391-30-0

Order Now

Specification Test Results

Purity 95%
Appearance/Color Solid.
Solubility Soluble in DMSO.


Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR