AT9283 ≥95%

Supplier: Van Der Voort Lucht en Milieu Amste

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102991-330EA 119.08 USD

102991-330 102991-332 102991-334 102991-336

AT9283 ≥95%

AT9283

Aurora kinases play a key role in the regulation of mitosis and in recent years have become attractive targets for the treatment of cancer. AT9283 is a powerful inhibitor of Aurora A and B kinases as well as several other important kinases including JAK2 and Abl (T315I). AT9283 has also been shown effective in mouise xenograft models and has been studied as a possible clinical candidate. Effective IC(50) doses for Aurora kinases are in the low 2-3nM range, and inhibition of a number of other kinases including JAK2 has been reported at 1-10nM.

Formula: C₁₉H₂₃N₇O₂
MW: 381.4 g/mol
Storage Temperature: Freezer

MDL Number: MFCD12031513
CAS Number: 896466-04-9

Specification Test Results

Purity	95%
Appearance/Color	Solid.
Solubility	Soluble in DMSO or ethanol.

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