(±)-Lisofylline ≥99% (by HPLC)

Supplier: Van Der Voort Lucht en Milieu Amste

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CDX-H0117-M010 CDX-H0117-M050

102990-124EA 78.92 USD

102990-124 102990-126

(±)-Lisofylline ≥99% (by HPLC)

(±)-Lisofylline

Synthetic methylxanthine metabolite of pentoxifylline. Potent anti-inflammatory agent in which only the (−) optical isomer is biologically active. Inhibits the generation of phosphatidic acid from cytokine-activated lysophosphatidic acyl transferase (LPAAT), which has been shown to protect mice from endotoxic shock. Decreases lipid peroxidation in vitr oand in vivo. Suppresses the production of the proinflammatory cytokine IFN-gamma, inhibits IL-12-mediated STAT-4 activation, enhances glucose-stimulated beta-cell insulin secretion, reducing the onset of diabetes in a non-obese diabetic mouse model, and blocks autoimmune deterioration of pancreatic beta cells in non-obese diabetic mice. Compound can be used as analytical reference material.

Formula: C₁₃H₂₀N₄O₃

MDL Number: MFCD00867573
CAS Number: 6493-06-7

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