N-Dodecanoyl-DL-homoserine lactone ≥97% (by GC)

Supplier: Van Der Voort Lucht en Milieu Amste

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CDX-D0339-M010 CDX-D0339-M050

102989-800EA 123.23 USD

102989-800 102989-802

N-Dodecanoyl-DL-homoserine lactone ≥97% (by GC)

N-Dodecanoyl-DL-homoserine lactone

N-Dodecanoyl-DL-homoserine lactone (C12-HSL) is a small diffusible signalling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism in bacteria. In addition to regulating bacterial functions, C12-HSL activates NF-kappaB in RAW 264.7 macrophages, increasing the expression of TNF-alpha, interleukin-1beta (IL-1beta) and IL-8, while other lactones do not. In addition, C12-HSL alters cell cycling and metabolism of human keratinocyte (HaCaT) cells. It also was shown to induce cell death by apoptosis.

Formula: C₁₆H₂₉NO₃
Storage Temperature: Refrigerator

MDL Number: MFCD03100412
CAS Number: 18627-38-8

Specification Test Results

Source/Host	Synthetic.
Purity	97% (GC)
Appearance/Color	White solid.
Solubility	Soluble in chloroform.

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