Herbimycin A ≥99% (by HPLC)

Supplier: Van Der Voort Lucht en Milieu Amste

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AG-CN2-0429-C100 AG-CN2-0429-M001

102988-250EA 207.69 USD

102988-250 102988-252

Herbimycin A ≥99% (by HPLC)

Herbimycin A

Benzoquinone ansamycin antibiotic

Source/Host: Isolated from Streptomyces sp.
Purity: >99% (HPLC)
Appearance/Color: Yellow solid.
Solubility: Soluble in ethanol, methanol DMSO or dimethylformamide. Poorly soluble in water.

Herbicidal compound. Potent, selective, irreversible and cell permeable protein tyrosine kinase inhibitor. Inhibitor of v-Src, Yes, Fps, Ros, Bcr-Abl and ErbB oncogene products. Antitumor compound. Antiangiogenic. Inhibits NF-kappaB activation and phosphorylation of phospholipase C-gamma1. Inhibitor of heat shock protein 90 (Hsp90). Binds Hsp90 and destabilizes client proteins leading to their ubiquitination and proteasomal degradation. Increases the sensitivity of certain cancer cells to chemotherapeutic agents. Neuroprotective. Antiparasitic, antischistosomal agent. Antiviral. Increase microtubules sensitivity to cold in plants.

Formula: C₃₀H₄₂N₂O₉
Storage Temperature: Freezer

MDL Number: MFCD00151702
CAS Number: 70563-58-5

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