Lactacystin ≥98% (by HPLC)

Supplier: Van Der Voort Lucht en Milieu Amste

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AG-CN2-0104-C100 AG-CN2-0104-C200 AG-CN2-0104-C500 AG-CN2-0104-M001

102987-354EA 96.92 USD

102987-354 102987-356 102987-358 102987-360

Lactacystin ≥98% (by HPLC)

Lactacystin

Induces neuritogenesis. Potent and selective irreversible proteasome inhibitor. Specifically inhibits 20S proteasome (MCP; multicatalytic complex). Blocks proteasome activity by targeting the catalytic beta-subunit. Apoptosis inducer. Anticancer compound. Upregulates HSP70 and HSP22. Induces differentiation and inhibits cell cycle progression in several tumor cell lines. Inhibits NF-kappaB activation by inhibiting IkappaB degradation. Cathepsin A inhibitor. beta-Secretase activity inhibitor. Anti-adipogenic. Autophagy inducer.

Formula: C₁₅H₂₄N₂O₇S
Storage Temperature: Freezer

CAS Number: 133343-34-7

Specification Test Results

Source/Host	Isolated from Streptomyces lactacystinnaeus strain OM-6519.
Purity	98% (HPLC)
Appearance/Color	White to off-white solid.
Solubility	Soluble in water, methanol, ethanol, DMSO, pyridine, acetonitrile or dimethyl formamide. Insoluble in hexane, benzene, chloroform or ethyl acetate.

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