cis-Platin
Supplier: Van Der Voort Lucht en Milieu AmsteTotal Ratings: 0
Avg. Ratings: 0.0 out of 5
Potent platinum-based antineoplastic agent. Anticancer compound. Forms inter- and intrastrand DNA adducts/crosslinks, consequently blocking DNA replication and transcription and inducing cell death. Nephrotoxic when used in vivo. Potent chemoimmunotherapeutic. Stimulates the immune responses by activating macrophages and other cells of the immune system. Apoptosis inducer via p53-dependent and -independent mechanisms. Induces apoptosis through caspase-3 activation and XIAP expression inhibition. Targets other proteins and enzymes. Non-competitive NHE-1 inhibitor, an archetypal, membrane-bound mechanosensitive sodium-hydrogen ion transporter.
Formula:
H₆Cl₂N₂Pt |
MDL Number:
MFCD00011623 CAS Number: 15663-27-1 UN: 3288 ADR: 6.1,II |
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