Chenodeoxycholic acid

Supplier: Van Der Voort Lucht en Milieu Amste

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AG-CN2-0410-M100 AG-CN2-0410-M500

102988-168EA 27.69 USD

102988-168 102988-170

Chenodeoxycholic acid

Chenodeoxycholic acid

Cytotoxic hydrophobic primary bile acid. Activator of farnesoid X receptor (FXR), a nuclear receptor that is hepatoprotective and regulates bile acid synthesis (cholesterol 7alpha-hydroxylase (CYP7A1) suppression), conjugation and transport, as well as genes involved in lipid and glucose metabolism and. Bile acid-controlled signaling pathways are promising novel targets to treat such metabolic diseases as obesity, type II diabetes, insulin resistance, hyperlipidemia and atherosclerosis. Inhibitor of 5beta-reductase (AKR1D1). Potent selective inhibitor of DD2 (AKR1C2). Potent inhibitor of 11beta-HSD1 dehydrogenase. Changes tumor cell viability via IL-6 pathway. Anticancer compound. Apoptosis inducer. Immunosuppressive and anti-inflammatory compound. Modulates oxidative stress. Differentiation regulator of mouse embryonic stem cells. Used for dissolution of cholesterol gallstones.

Formula: C₂₄H₄₀O₄

MDL Number: MFCD00064142
CAS Number: 474-25-9

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