Aphidicolin (from Phoma sp. BS 7210) ≥98% (by HPLC)
Supplier: Van Der Voort Lucht en Milieu AmsteTotal Ratings: 0
Avg. Ratings: 0.0 out of 5
(+)-Aphidicolin is a reversible inhibitor of eukaryotic nuclear DNA replication.
- Useful for cell synchronization
- Antibiotic
- Antileishmanial agent
Phytotoxin. Antibiotic. Antiviral and antineoplastic agent. Blocks the cell cycle at G1/S phase. Prolongs the half life of DNA methyltransferase. DNA methylation/demethylation modulator. Specific DNA polymerase alpha and delta inhibitor in eukaryotic cells and in some viruses of animal origin. Acts synergistically with vincristine and doxorubicin. Apoptosis inhibitor/inducer.
White to off-white solid
After reconstitution protect from light at -20°C. Stable for at least one year after receipt when stored at +4°C.
Soluble in DMSO (50 mg/ml), methanol (10 mg/ml) or 100% ethanol; insoluble in water.
Formula:
C₂₀H₃₄O₄ Storage Temperature: Refrigerator |
MDL Number:
MFCD00083214 CAS Number: 38966-21-1 |
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