Concanamycin A (from Streptomyces species) ≥98% (by HPLC), high purity
Supplier: Van Der Voort Lucht en Milieu AmsteTotal Ratings: 0
Avg. Ratings: 0.0 out of 5
Concanamycin A is an antibiotic isolated from Streptomyces sp. which is a more potent and specific H⁺ -ATPase inhibitor than Bafilomycin A₁. It inhibits acidification of organelles, such as lysosomes and the Golgi apparatu,s and blocks cell surface expression of viral glycoproteins without affecting their synthesis.
- Cytotoxic
- Induces nitric oxide (NO) production
- Autophagy inhibitor
Antibiotic. More potent and specific H+-ATPase inhibitor than bafilomycin A1. Blocks cell surface expression of viral glycoproteins without affecting their synthesis. Cytotoxic in a number of cell lines in a cell viability assay. Induces nitric oxide (NO) production. Autophagy inhibitor. Short term storage at 4 °C.
White to off-white solid
After reconstitution protect from light at -20°C. Stable for at least one year after receipt when stored at -20°C.
Soluble in methanol, DMSO or acetonitrile; insoluble in water.
Formula:
C₄₆H₇₅NO₁₄ MW: 866.1 g/mol Storage Temperature: Freezer |
CAS Number:
80890-47-7 |
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