Rebeccamycin (from Streptomyces ramulosus) ≥98% (by HPLC)
Supplier: Van Der Voort Lucht en Milieu AmsteTotal Ratings: 0
Avg. Ratings: 0.0 out of 5
Rebeccamycin is a weak topoisomerase I (Topo I) inhibitor.
- Significant anti-tumor properties in vitro
- Antibiotic
- Structurally similar to staurosporine
Antibiotic. Does not show any inhibitory activity against protein kinases. Shows significant antitumor properties in vitro (IC50 = 480 nM against mouse B16 melanoma cells and IC50 = 500 nM against P388 leukemia cells).
Yellow solid
After reconstitution, prepare aliquots and store at -20°C. Stable for at least one year after receipt when stored at -20°C. Stock solutions are stable for at least three months when stored at -20°C
Soluble in DMSO or methanol
MW:
570.4 g/mol Storage Temperature: Freezer |
CAS Number:
93908-02-2 |
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