Demecolcine ≥98% (by HPLC)

Supplier: Van Der Voort Lucht en Milieu Amste

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AG-CR1-3567-M001 AG-CR1-3567-M005

102516-304EA 41.54 USD

102516-304 102516-306

Demecolcine ≥98% (by HPLC)

Demecolcine

Anti-cancer compound. Cell synchronization agent. Used as a drug in chemotherapy by synchronizing tumor cells at metaphase, the radiosensitive stage of the cell cycle. Microtubule assembly inhibitor. Depolymerizes microtubules and limits microtubule formation (inactivates spindle fibre formation). Inhibits mitosis during cell division at metaphase by inhibiting spindle formation. Low concentrations affect microtubule dynamics and cell migration, while high concentrations promote microtubule detachment from microtubule organizing center. Apoptosis inducer. Thrombopoietic agent.

Formula: C₂₁H₂₅NO₅
Storage Temperature: Freezer

MDL Number: MFCD00075459
CAS Number: 477-30-5
UN: 2811
ADR: 6.1,III

Specification Test Results

Source/Host	Semisynthetic from colchicine (Prod. No. AG-CN2-0048).
Purity	98% (HPLC)
Appearance/Color	White to off-white powder.
Solubility	Soluble in ethanol, DMSO or chloroform.

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