Human Recombinant Netrin-1 (from HEK293 Cells)

Supplier: Van Der Voort Lucht en Milieu Amste

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AG-40B-0075-C010 AG-40B-0075-3010 AG-40B-0075-C100

102515-542EA 401.54 USD

102515-542 102980-128 102980-130

Human Recombinant Netrin-1 (from HEK293 Cells)

Proteins and Peptides

Netrin-1 controls guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Netrin-1 is also Involved in tumorigenesis by regulating apoptosis. Netrin-1 promotes atherosclerosis by retaining macrophages in the artery wall. Netrin-1 also governs induced pluripotent stem cell (iPS) formation and improves reprogramming efficiency of human and mouse somatic cells by limiting apoptosis mediated by Netrin-1 receptors DCC or UNC5b.

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