Parthenolide ≥97% (by TLC)

Supplier: SAFE AND SURE NEDERLAND B.V.

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Parthenolide ≥97% (by TLC)

Parthenolide ≥97% (by TLC)

BML-T113-0050 BML-T113-0250

89164-978EA 112.27 USD

89164-978 89164-980

Parthenolide ≥97% (by TLC)

Parthenolide

HDAC inhibitor

Sesquiterpene lactone. Widely used as an herbal remedy for arthritis and migraine. Has anti-inflammatory, antisecretory and spasmolytic activity. Specifically inhibits activation of NF-kappaB by preventing the degradation of IkappaBalpha and IkappaBbeta. Inhibits activation of MAP kinase (MAPK/ERK) and generation of leukotriene B4 and thromboxane B2. Potent anticancer agent. Induces apoptosis in various cancer cell lines. Specifically inhibits histone deacetylase 1 (HDAC1) without affecting other class I/II HDACs. Inhibits tubulin carboxypeptidase (TCP) activity.

Isolated from feverfew (Chrysanthemum parthenium) leaves.

Formula: C₁₅H₂₀O₃
MW: 248.32 g/mol

MDL Number: MFCD00134592
CAS Number: 20554-84-1

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