DMOG ≥99% (by TLC)
Supplier: SAFE AND SURE NEDERLAND B.V.Total Ratings: 0
Avg. Ratings: 0.0 out of 5
DMOG is a cell permeable prolyl-4-hydroxylase inhibitor which upregulates HIF activity. HIF activation stimulates angiogenesis in several different models. DMOG also inhibits FIH (Factor Inhibiting HIF), an asparaginyl hydroxylase, which enhances the HIF response. It is active in vivo and attenuates myocardial injury in a rabbit ischemia reperfusion model (20mg/kg). Is expected to act pro-angiogenic.
- Prolyl-4-hydroxylase inhibitor
Off-white solid.
Soluble in DMSO (>25mg/ml), 100% ethanol (>25mg/ml) or dimethyl formamide; soluble also in PBS, pH7.2 (10mg/ml).
Formula:
C₆H₉NO₅ |
MDL Number:
MFCD05865098 CAS Number: 89464-63-1 |
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