Apigenin ≥97% (by TLC)

Supplier: SAFE AND SURE NEDERLAND B.V.

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Apigenin ≥97% (by TLC)

Apigenin ≥97% (by TLC)

BML-EI345-0020 BML-EI345-0100

89158-136EA 119.9 USD

89158-136 89158-138

Apigenin ≥97% (by TLC)

Apigenin

Antioxidant and chemopreventive

Apigenin is an antioxidant flavonoid. Has chemopreventive and antitumor properties. Induces apoptosis. Inhibits the proliferation of malignant tumor cells by G2/M arrest. Is a MAP-Kinase (MAPK/ERK) inhibitor. Inhibits hypoxia-inducible factor-1 (HIF-1) and vascular endothelial growth factor (VEGF) expression. Induces gastric relaxation in mouse stomach, mainly by suppressing Ca2+ influx through voltage-dependent calcium channels. Apigenin is a selective inhibitor of CK2. In WEHI 231 cells inhibition of CK2 by apigenin decreased the rate of IκBα turnover and nuclear levels of NF-κB (20 µM). It blocks proliferation of Wnt-1 transfected cells and abrogates phosphorylation of β-catenin. In a rat model of glomerulonephritis, inhibition of CK2 by apigenin ameliorates renal dysfunction.

Formula: C₁₅H₁₀O₅

MDL Number: MFCD00006831
CAS Number: 520-36-5

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