PP1 ≥98% (by TLC)
Supplier: SAFE AND SURE NEDERLAND B.V.
Ratings:
(No Reviews)
Total Ratings: 0
Avg. Ratings: 0.0 out of 5
BML-EI275-0001
BML-EI275-0005
89157-942EA
127.53
USD
89157-942
89157-944
PP1 ≥98% (by TLC)
PP1
Src kinase inhibitor
A highly potent and selective inhibitor of Src family tyrosine kinases, IC50=5 nM for p56lck; p59fynT=6 nM; p60src=170 nM. Inhibition of Src family kinases by PP1 has been shown to: prevent a-thrombin-stimulated Akt phosphorylation, delay PAF-mediated STAT3 phosphorylation, block Zn2+-induced Ras activation, block adhesion-dependent tyrosine phosphorylation of p105HEF1 5, and inhibit HLA-DR-induced tyrosine phosphorylation without affecting the activation of ERK1/2.
Formula:
C₁₆H₁₉N₅ MW: 281.4 g/mol |
MDL Number:
MFCD01076570 CAS Number: 172889-26-8 |
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