Fasudil dihydrochloride ≥98% (by TLC)

Supplier: SAFE AND SURE NEDERLAND B.V.

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Fasudil dihydrochloride ≥98% (by TLC)

Fasudil dihydrochloride ≥98% (by TLC)

BML-EI233-0010 BML-EI233-0050

89157-834EA 184.21 USD

89157-834 89157-836

Fasudil dihydrochloride ≥98% (by TLC)

Fasudil dihydrochloride

Inhibits Rho kinase (ROCK; Ki=0.33μM). Selective protein kinase A and G inhibitor (both Ki’s = 1.6μM). Inhibits agonist-induced activation of NADPH oxidase in human neutrophils (IC50=15μM). Inhibitor of myosin light chain kinase and Ca2+/calmodulin-dependent protein kinase II. Inhibits translocation of PKCβI, PKCβII and PKCζ. Cell permeable Ca2+ antagonist with antivasospastic properties.

Rho kinase (ROCK) inhibitor

White to off-white solid.

Soluble in water (>20mg/ml), methanol or DMSO.

Formula: C₁₄H₁₇N₃O₂S·2HCl
MW: 364.29 g/mol
Melting Pt: 238…242 °C
Storage Temperature: Freezer

MDL Number: MFCD00153805
CAS Number: 203911-27-7

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