Embelin ≥98%
Supplier: SAFE AND SURE NEDERLAND B.V.
Ratings:
(No Reviews)
Total Ratings: 0
Avg. Ratings: 0.0 out of 5
BML-CM125-0010
BML-CM125-0050
89156-972EA
103.55
USD
89156-972
89156-974
Embelin ≥98%
Embelin
XIAP inhibitor
Embelin is a novel cell-permeable inhibitor of XIAP (X-linked inhibitor of apoptosis) which was discovered by screening a library of natural products derived from traditional Chinese medicine. It binds to the XIAP BIR3 domain preventing its binding to and inhibition of caspase-9 and effector caspases. Embelin selectively inhibits cell growth in cancer cells expressing high levels of XIAP (IC50 = 3-6 µM) versus normal cells with low levels of XIAP.
Formula:
C₁₇H₂₆O₄ |
MDL Number:
MFCD00016369 CAS Number: 550-24-3 |
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