Embelin ≥98%

Supplier: SAFE AND SURE NEDERLAND B.V.
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BML-CM125-0010 BML-CM125-0050
89156-972EA 103.55 USD
89156-972 89156-974
Embelin ≥98%
Embelin

XIAP inhibitor


Embelin is a novel cell-permeable inhibitor of XIAP (X-linked inhibitor of apoptosis) which was discovered by screening a library of natural products derived from traditional Chinese medicine. It binds to the XIAP BIR3 domain preventing its binding to and inhibition of caspase-9 and effector caspases. Embelin selectively inhibits cell growth in cancer cells expressing high levels of XIAP (IC50 = 3-6 µM) versus normal cells with low levels of XIAP.

Formula: C₁₇H₂₆O₄
MDL Number: MFCD00016369
CAS Number: 550-24-3

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