SKF-96365 hydrochloride ≥98% (by HPLC)
Supplier: SAFE AND SURE NEDERLAND B.V.Total Ratings: 0
Avg. Ratings: 0.0 out of 5
A novel, selective inhibitor of receptor-mediated calcium entry. It inhibits receptor-mediated calcium entry in stimulated platelets (IC50=8-12µM) neutrophils and endothelial cells at concentrations which do not affect internal Ca2+ release. Note, in some cells SK&F 96365 can activate a novel Ca2+ entry pathway. Blocks TRPC3 and TRPC6 activation. Inhibits the histamine-induced formation of nitric oxide in human endothelial cells.
- TRP channel blocker
White solid.
Soluble in water (30mg/ml).
Formula:
C₂₂H₂₆N₂O₃·HCl Melting Pt: 117…119 °C Storage Temperature: Ambient |
MDL Number:
MFCD00236407 CAS Number: 130495-35-1 |
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