Necrostatin-1 ≥98% (by TLC)

Supplier: SAFE AND SURE NEDERLAND B.V.
Ratings: (No Reviews)

Total Ratings: 0
Avg. Ratings: 0.0 out of 5

BML-AP309-0020 BML-AP309-0100
89156-600EA 163.5 USD
89156-600 89156-602
Necrostatin-1 ≥98% (by TLC)
Necrostatin-1

Inhibits necroptosis


Necrostatin-1 inhibits necroptosis, a non-apoptotic cell death pathway. Inhibits the loss of mitochondrial membrane potential in TNFα-treated Jurkat cells (EC50=490 nM). Does not inhibit FAS-induced apoptosis and has no effect on apoptotic morphology. It displays a pronounced protective effect in a mouse model of ischemic brain injury and inhibits myocardial cell death. Inhibits RIP1 kinase the key upstream kinase involved in the activation of necroptosis (EC50=180nM).

Formula: C₁₃H₁₃N₃OS
MDL Number: MFCD00056916
CAS Number: 4311-88-0

Order Now


Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR