MPLA S. minnesota 99,9, TLRgrade™

Supplier: SAFE AND SURE NEDERLAND B.V.

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581-202-L001 581-202-R500

89152-794EA 604.95 USD

89152-794 76002-220

MPLA S. minnesota 99,9, TLRgrade™

MPLA

TLR4 activator.

Isolated from Salmonella minnesota R595 (Re mutant). Prepared by acid hydrolysis from purified Salmonella minnesota R595 (Re) LPS (isolated by a modification of the PCP extraction method), converted to the uniform salt form.

Activates Toll-like receptor (TLR) 4. Does not activate TLR2 as determined with splenocytes and macrophages from TLR4 deficient mice. Exhibits reduced endotoxic and pyrogenic activity compared to lipid A and LPS.

Synonym: MPL-A from Salmonella minnesota R595 (Re).

Specification Test Results

Concentration	1 mg/ml
Formulation	Liquid. Sterile, ready-to-use solution in pyrogen-free double distilled water
Purity	≥99.9% (regarding protein or DNA contaminants, KDO not detectable)

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