A77 1726 ≥98% (by HPLC)
Supplier: SAFE AND SURE NEDERLAND B.V.
Ratings:
(No Reviews)
Total Ratings: 0
Avg. Ratings: 0.0 out of 5
430-096-M005
430-096-M025
89151-098EA
80.66
USD
89151-098
89151-100
A77 1726 ≥98% (by HPLC)
A77 1726
Dihydrorotate dehydrogenase inhibitor
Physiologically active metabolite of the immunosuppressive drug leflunomide (Prod. No. ALX-430-095). Inhibits the activity of dihydrorotate dehydrogenase and of protein tyrosine kinases. Blocks TNF-mediated NF-kappaB activation in a dose- and time-dependent manner. Also inhibits the activity of cyclooxygenase-2 (COX-2) in vitro and in vivo.
Formula:
C₁₂H₉F₃N₂O₂ |
MDL Number:
MFCD00910058 CAS Number: 108605-62-5 |
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