Amidepsine A ≥95% (by HPLC)
Supplier: SAFE AND SURE NEDERLAND B.V.
Ratings:
(No Reviews)
Total Ratings: 0
Avg. Ratings: 0.0 out of 5
380-262-M001
380-262-MM25
89150-286EA
407.66
USD
89150-286
89150-288
Amidepsine A ≥95% (by HPLC)
Amidepsine A
DGAT inhibitor
Inhibitor of diacylglycerol acyltransferase (DGAT). Shows inhibitory effect in rat liver microsomes (IC50=10.2µM) and Raji cells (IC50=15.5µM). Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.
Isolated from fungal strain FO-2943.
Ordering information: Fungal strain courtesy of the Kitasato Institute, Tokyo.
Formula:
C₂₉H₂₉NO₁₁ |
CAS Number:
169181-28-6 |
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