Amidepsine A ≥95% (by HPLC)

Supplier: SAFE AND SURE NEDERLAND B.V.
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380-262-M001 380-262-MM25
89150-286EA 407.66 USD
89150-286 89150-288
Amidepsine A ≥95% (by HPLC)
Amidepsine A

DGAT inhibitor


Inhibitor of diacylglycerol acyltransferase (DGAT). Shows inhibitory effect in rat liver microsomes (IC50=10.2µM) and Raji cells (IC50=15.5µM). Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.


Isolated from fungal strain FO-2943.


Ordering information: Fungal strain courtesy of the Kitasato Institute, Tokyo.

Formula: C₂₉H₂₉NO₁₁
CAS Number: 169181-28-6

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