Betulinic acid ≥99%, high purity

Supplier: SAFE AND SURE NEDERLAND B.V.

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Betulinic acid ≥99%, high purity

Betulinic acid ≥99%, high purity

350-277-M005 350-277-M025

89149-396EA 51.23 USD

89149-396 89149-398 89149-400

Betulinic acid ≥99%, high purity

Betulinic acid

Antitumor and anti-HIV agent

Antitumor and anti-HIV agent. Induces apoptosis by activating mitochondrial permeability transition (MPT). Inhibits NF-κB activation and NF-κB-regulated gene expression induced by carcinogens and inflammatory stimuli. Decreases expression of Bcl-2 and cyclin D1. Potent proteasome activator. Triggers CD95- and p53-independent apoptosis via activation of caspases. It induces mitochondrial permeability pore opening and the release of cytochrome c and apoptosis-inducing factor. Displays anti-HIV activity. EC50 for inhibion of HIV-1 replicaton in H9 lymphocytes: 1.4µM.

Isolated from Platanus acerifolia (plane) tree bark.

Formula: C₃₀H₄₈O₃

MDL Number: MFCD00009619
CAS Number: 472-15-1

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