PD 184,352 ≥95% (by HPLC, NMR)
Supplier: SAFE AND SURE NEDERLAND B.V.
Ratings:
(No Reviews)
Total Ratings: 0
Avg. Ratings: 0.0 out of 5
270-471-M001
270-471-M005
89148-018EA
147.15
USD
89148-018
89148-020
PD 184,352 ≥95% (by HPLC, NMR)
PD 184,352
Potent and selective inhibitor of MAPK (ERK kinase 1; MEK1) activation (IC50=300nM in vitro, IC50=2nM in vivo). Suppresses activation of MAPK but does not block its activity. Strongly suppresses growth of human implanted colon tumors in mice.
Synthetic.
Formula:
C₁₇H₁₄ClF₂IN₂O₂ MW: 478.7 g/mol |
MDL Number:
MFCD02683961 CAS Number: 212631-79-3 |
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