Sirtinol ≥97% (by NMR)

Supplier: SAFE AND SURE NEDERLAND B.V.
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270-308-M001 270-308-M005
89147-612EA 49.05 USD
89147-612 89147-614
Sirtinol ≥97% (by NMR)
Sirtinol

SIRT inhibitor


Specific cell permeable inhibitor of the sirtuin family of NAD-dependent deacetylases (ySir2: IC50=48µM; hSIRT1: IC50=60µM; hSIRT2: IC50=58µM) with no effect on human HDAC1. Reported to inhibit Sir2p transcriptional silencing activity in vivo (IC50=25µM) and NAD-dependent histone deacetylase activity of purified recombinant yeast Sir2p (IC50=70µM) and hSIRT2 (IC50=40µM) in vitro.

Formula: C₂₆H₂₂N₂O₂
MW: 394.46 g/mol
MDL Number: MFCD00810186
CAS Number: 410536-97-9

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