Toluene-α-sulfonyl fluoride ≥99% (by GC-FID)

Supplier: SAFE AND SURE NEDERLAND B.V.

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Avg. Ratings: 0.0 out of 5

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Synonyms: PMSF, Phenylmethanesulphonyl fluoride, Phenylmethylsulphonyl fluoride, α-Toluenesulfonyl fluoride, α-Toluenesulphonyl fluoride, Phenylmethanesulfonyl fluoride, Phenylmethylsulfonyl fluoride

270-184-G005 270-184-G025

89147-336EA 81.8 USD

89147-336 89147-338

Toluene-α-sulfonyl fluoride ≥99% (by GC-FID)

Toluene-α-sulphonyl fluoride

Irreversible inhibitor of serine proteases. Widely used fatty acid amid hydrolase (FAAH) inhibitor for pretreatment of brain membrane preparations when testing CB1 receptor activity. Spleen membranes used for CB2 studies do not require this pretreatment, as FAAH activity is absent in these cells. Inhibits also cysteine proteases like papain (reversible by DTT treatment, Prod. No. ALX-280-001), as well as internucleosomal DNA fragmentation in immature thymocytes. For a related, more stable inhibitor see AEBSF.

Inhibitor of serine proteases and FAAH

White to off-white needle crystals.

Soluble in 100% ethanol, methanol or isopropanol; insoluble in water.

Formula: C₇H₇FO₂S
MW: 174.2 g/mol
Storage Temperature: Ambient

MDL Number: MFCD00007424
CAS Number: 329-98-6

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