Anti-CaN Rabbit Polyclonal Antibody

Supplier: Enzo Life Sciences

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Anti-CaN Rabbit Polyclonal Antibody

Anti-CaN Rabbit Polyclonal Antibody

ADI-SPA-610-D ADI-SPA-610-F

95057-954EA 222.36 USD

95057-954 95057-956

Anti-CaN Rabbit Polyclonal Antibody

Antibodies

Calcineurin is a Ca2+/Calmodulin-dependent serine/threonine protein phosphatase. The active enzyme is a heterodimer consisting of a catalytic A subunit and a myristylated regulatory B subunit that binds calcium. Calcineurin, which is the target of immunosuppressant drugs such as cyclosporin A and FK506, controls the translocation of Nuclear factors of activated T-cells (NFAT), a family of transcriptional activators that control the expression of cytokine genes essential to immune response, from the cytosol into the nucleus of activated T-cells.

For Immunoprecipitation, Western Blot

Recognizes human, mouse, rat, bovine, dog, chicken, Drosophila, hamster, monkey, pig, rabbit and sheep calcineurin A. Detects a band of ~61kDa by Western blot.

Type: Primary
Antigen: CaN
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human

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