Anti-CASP3 Rabbit Polyclonal Antibody

Supplier: Enzo Life Sciences

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Anti-CASP3 Rabbit Polyclonal Antibody

Anti-CASP3 Rabbit Polyclonal Antibody

ADI-AAS-103-D ADI-AAS-103-F

95045-890EA 217 USD

95045-890 95045-892

Anti-CASP3 Rabbit Polyclonal Antibody

Antibodies

The caspases are a family of cysteine proteases that cleave after certain aspartate residues, and are primarily recognized as mediators of apoptosis. caspases are synthesized as inactive zymogens that can be cleaved to form active enzymes following the induction of apoptosis by stress or death receptors. Initiator caspases (e.g. caspase-8 and -10) are activated by dimerization of the zymogen on a dedicated adaptor protein. These activated initiator caspases in-turn cleave downstream effector or ?executioner? caspases (e.g. caspase-3, -6, and -7) in a cascade-like manner, which cleave key cellular proteins that lead to the morphological changes associated with apoptotic cell death.

For Western Blot

Recognizes human, mouse, rat, bovine, dog, chicken, guinea pig, hamster, monkey, pig, rabbit, sheep and Xenopus Caspase-3. Detects a band of ~36kDa by Western blot.

Type: Primary
Antigen: CASP3
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human

Q and A

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