Mouse;Rat Galanin

Supplier: Frontier Scientific
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4030645.0500 4030645.1000
H-7450.0500BAEA 408.5 USD
H-7450.0500BA H-7450.1000BA
Mouse;Rat Galanin
Proteins and Peptides

The isolation and characterization of cDNAs encoding rat galanin and its precursor peptide reveal that rat galanin is synthesized initially as part of a 124-amino acid precursor that includes a signal peptide, galanin, and a 60-amino acid galanin mRNA-associated peptide. The neuropeptide galanin shows multiple inhibitory actions on neurotransmission and memory. In Alzheimer's disease, increased galanin-containing fibers hyperinnervate cholinergic neurons within the basal forebrain in association with a decline in cognition.

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