Non-Abeta Component of Alzheimer's Disease Amyloid Trifluoroacetate
Supplier: Frontier Scientific
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4026207.0500
4026207.1000
H-2598.0500BAEA
605.77
USD
H-2598.0500BA
H-2598.1000BA
Non-Abeta Component of Alzheimer's Disease Amyloid Trifluoroacetate
Proteins and Peptides
The 35 amino acid peptide NAC (α-synuclein (61-95)) has originally been isolated from the insoluble core of Alzheimer's disease (AD) amyloid plaque. The sequence corresponds to a fragment of a 140 amino acid precursor known as NACP or α-synuclein and was found to form amyloid fibrils via a nucleation-dependent polymerization mechanism. Accumulation of NAC aggregates in the synapse might be responsible for the neurodegeneration in AD and in the prion diseases.
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