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You Searched For: 5-[(4-Propyloxyphenyl)methylene]-2,4-thiazolidinedione (SMI-16a)


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5-[(4-Propyloxyphenyl)methylene]-2,4-thiazolidinedione (SMI-16a) 98%

Supplier: AMBEED, INC
Description: 5-(4-propoxybenzylidene)thiazolidine-2,4-dione, Purity: 98%, CAS Number: 587852-28-6, Appearance: Solid, Storage: Keep in dark place, Sealed in dry, 2-8 C, Size: 10mg

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5-[(4-Propyloxyphenyl)methylene] 2,4-thiazolidinedione ≥95% (by HPLC)

Supplier: Adipogen
Description: Potent, cell-permeable, ATP-competitive inhibitor of Pim-1/2 kinases (IC50 = 150 nM and 20 nM against Pim-1 and Pim-2, respectively) as well as DYRK1alpha (68% inhibition of DYRK1alpha and Pim-2 at 5 µM), while exhibiting little or no activity against a panel of 57 other kinases (<lt/>18% inhibition at 5 µM). Reported to exhibit antitumor activity in PC3 human prostate cancer cultures in vitro (IC50 = 48 µM) and in JC adenocarcinoma-transplanted Balb/C mice in vivo (~46% tumor mass reduction on day 20| 50 mg/kg via daily i.p.).

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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