AZD1208 ≥95%

Supplier: Van Der Voort Lucht en Milieu Amste
Ratings: (No Reviews)

Total Ratings: 0
Avg. Ratings: out of 5

SYN-1214-M001 SYN-1214-M005 SYN-1214-M010 SYN-1214-M050 SYN-1214-M100
102992-830EA 90 USD
102992-830 102992-832 102992-834 102992-836 102992-838
AZD1208 ≥95%
AZD1208

Potent, highly selective and orally available Pim kinase inhibitor that effectively inhibits all three isoforms Pim-1, Pim-2 and Pim-3 at 5nM or 150 nM in enzyme and cell assays, respectively. Potently inhibits colony growth and Pim signalling substrates in primary AML cells from bone marrow that are Flt3 wild-type or Flt3 internal tandem duplication mutants. Upregulation of Pim kinases is observed in several types of leukemias and lymphomas. Pim-1, -2 and -3 promote cell proliferation and survival downstream of cytokine and growth factor signaling pathways.

Formula: C₂₁H₂₁N₃O₂S
MW: 379.5 g/mol
Storage Temperature: Freezer
MDL Number: MFCD25976757
CAS Number: 1204144-28-4

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Specification Test Results

Purity 95%
Appearance/Color Solid.
Solubility Soluble in DMSO.


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