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Description: The Pax gene family of nuclear transcription factors comprises nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).

CF® dyes are Biotium's next-generation fluorescent dyes. CF®543 is an orange fluorescent dye (Ex/Em 541/560 nm) designed for the 543 nm laser line. It yields the brightest conjugates among spectrally similar dyes.

Catalog Number: 75968-952

Supplier: Biotium

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Description: Complement C4d Monoclonal antibody, Clone: TDM16, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF640R, Immunogen: Human Complement 4d protein, Application: Immunofluorescence, Flow cytometry, Size: 100uL

Catalog Number: 75921-402

Supplier: Biotium

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Description: CD56 / NCAM Monoclonal antibody, Clone: 123C3.D5, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: CF568, Immunogen: Membrane preparation of a small cell lung carcinoma, Synonyms: NCAM, Leu-19, NKH1, Size: 500 uL

Catalog Number: 75914-574

Supplier: Biotium

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Description: Blue Fluorescent Cf350 (Ex/Em 347/448) Is Spectrally Similar To Amca And Alexafluor 350, With Superior Brightness

Catalog Number: 89427-154

Supplier: Biotium

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Description: This antibody recognizes 78 kDa moesin protein. Moesin, a member of the talin-4.1 superfamily, is a linking protein of the sub-membranous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.

Catalog Number: 75885-924

Supplier: Biotium

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Description: Membrane-permeant form of Rhod-590 calcium indicator dye that can be loaded into cells via incubation. Because of the relatively low water solubility of the AM ester, Pluronic F-127, a mild detergent, is often used as a dispersing agent to facilitate dye loading. Rhod-590 AM ester itself does not bind Ca2 , but it is readily hydrolyzed to Rhod-590 by endogenous esterases once it enters cells.

Catalog Number: 10018-200

Supplier: Biotium

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Description: MUC18 / Mucin 18 / CD146, Monoclonal antibody, Clone: MUC18/1130, Host: Mouse, Species reactivity: Human, Isotype: IgG3, kappa, Conjugate: CF405S, Immunogen: Recombinant human MUC18 protein, Application: IF, Immunohistology (formalin), Flow, Size: 500uL

Catalog Number: 75964-132

Supplier: Biotium

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Description: Vimentin, Monoclonal antibody, Clone: VM1170, Host: Mouse, Species reactivity: Mouse, Pig, Cow, Cat, Sheep, Rat, Human, Rabbit, Isotype: IgM, Conjugate: CF640R, Immunogen: Human thymic nuclear extract, Synonyms: VIM, Application: IF, Size: 100uL

Catalog Number: 75979-122

Supplier: Biotium

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Description: CD33 Monoclonal antibody, Clone: C33/68, Host: Mouse, Conjugate: CF405S, Species reactivity: Human, Immunogen: Recombinant human CD33 protein, Isotype: IgG1, kappa, Synonyms:gp67, Application: IF, FC, Size: 100uL

Catalog Number: 75893-432

Supplier: Biotium

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Description: S100A9, Monoclonal antibody, Clone: S100A9/1075, Host: Mouse, Species reactivity: Human, Rat, Isotype: IgM, BSA-free, Immunogen: Human peripheral blood monocyte components, Application: Immunofluorescence, Immunohistology (formalin), Flow cytometry, Size: 50 uL

Catalog Number: 75974-024

Supplier: Biotium

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Description: is labeled w/ deep-red fluorescent dye CF594 which is spectrally similar to Alexa Fluor 594 & Texas Red dyes but yields brighter protein conjugates. CF594 has photostability ideal for demanding applications such as multi-color imaging.

Catalog Number: 89138-624

Supplier: Biotium

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Description: Anti-IgG Donkey Antibody (CF™ 568)

Catalog Number: 89493-172

Supplier: Biotium

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Description: Calponin-1 Monoclonal antibody, Clone: CALP + CNN1/832, Host: Mouse, Species reactivity: Human, Rat, Isotype: IgG1, kappa, Conjugate: CF488A, Immunogen: Recom full-length human CNN1 ; Crude human uterus extract, Synonyms: CNN1, Cnn1, Application: IF, Size: 100uL

Catalog Number: 75883-062

Supplier: Biotium

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Description: Cyclin A2 Monoclonal antibody, Clone: E67, Host: Mouse, Species reactivity: Mouse, Mink, Green monkey, Monkey, Cow, Human, Isotype: IgG1, kappa, Conjugate: BSA-free, Immunogen: Full length bovine Cyclin A, Synonyms: CCN1, CCNA, CCNA2, Application: IF, Size: 50 uL

Catalog Number: 75921-476

Supplier: Biotium

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Description: ANTS (8-aminonaphthalene-1,3,6-trisulfonic acid, disodium salt) is a highly negatively charged dye with an amino group that can be coupled to an aldehyde or ketone group to form an unstable Schiff base. The Schiff base is usually chemically reduced by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaB(CN)H3) to form a stable linkage. This labeling technique has been widely used for the labeling and subsequent sequencing of oligosaccharides and glycoproteins. The negative charges of the dye facilitate the electrophoretic separation of the degradation products of carbohydrate polymers.

Catalog Number: 89139-534

Supplier: Biotium

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Description: CD106 / VCAM1 Monoclonal antibody, Clone: 1.4C3, Host: Mouse, Species reactivity: Human, Isotype: IgG1, kappa, Conjugate: biotin, Immunogen: Stimulated human umbilical vein endothelial cells, Synonyms: CD106, INCAM-100, L1CAM, Application: IF, Size: 500 uL

Catalog Number: 75884-088

Supplier: Biotium

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