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Crystal Digital PCR® Assay for BRAF (V600, V600E)

Supplier: STILLA TECHNOLOGIES, INC.
Description: Assay-specific Crystal Flex Probes and primers for the detection of BRAF mutations and its Positive Control. BRAF (V600, V600E) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 1 mutation in the BRAF gene using the Ruby Chip. BRAF is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma, colorectal cancer and thyroid cancer, through its role in the MAPK/ERK pathway. Mutations in BRAF, particularly the V600E mutation, lead to uncontrolled cell proliferation and survival.

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Stilla® naica® multiplex PCR MIX

Supplier: STILLA TECHNOLOGIES, INC.
Description: The naica® mutliplex PCR MIX is a ready-to-use two-component solution specifically formulated for optimal TaqMan® fluorescent probe-based Crystal Digital PCR®.

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Crystal Digital PCR® Assay for NRAS (drop-off G12-G13)

Supplier: STILLA TECHNOLOGIES, INC.
Description: Assay-specific crystal flex probes and primers for the detection of NRAS mutations and its positive control. The NRAS (drop-off G12-G13) Crystal Digital PCR® assay is a 10X assay designed to detect and quantify mutations in codons 12 and 13 of the NRAS gene using the ruby chip. NRAS is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma and colorectal cancer.

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Crystal Digital PCR® Assay for TP53 (drop-off V272-A276/R283-E286)

Supplier: STILLA TECHNOLOGIES, INC.
Description: Assay-specific Crystal Flex Probes and primers for the detection of TP53 mutations and its positive control. TP53 (drop-off V272-A276/R283-E286) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify mutations between V272-A276 or R283-E286 of the TP53 gene using the Ruby Chip. TP53 is pivotal in regulating cell divisison, thus an important tumor suppressor gene.

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Crystal Digital PCR® Assay for BRAF (V600, V600E, V600K)

Supplier: STILLA TECHNOLOGIES, INC.
Description: Assay-specific Crystal Flex Probes and primers for the detection of BRAF mutations and its Positive Control. BRAF (V600, V600E, V600K) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 2 mutations in the BRAF gene using the Ruby Chip. BRAF is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma, colorectal cancer and thyroid cancer, through its role in the MAPK/ERK pathway. Mutations in BRAF, particularly the V600E mutation, lead to uncontrolled cell proliferation and survival.

New Product

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Crystal Digital PCR® Assay for ESR1 (17 Mutations)

Supplier: STILLA TECHNOLOGIES, INC.
Description: Assay-specific Crystal Flex Probes and primers for the detection of ESR1 mutations and its positive control. ESR1 (17 mutations) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 17 mutations in the ESR1 gene using the Ruby Chip. ESR1 is pivotal in mediating resistance to endocrine therapy in metastatic hormone-positive breast cancer.

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Crystal Digital PCR® Assay for PIK3CA (H1047, H1047R)

Supplier: STILLA TECHNOLOGIES, INC.
Description: Assay-specific Crystal Flex Probes and primers for the detection of PIK3CA mutations and its positive control. The PIK3CA (H1047, H1047R) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 1 mutation in the PIK3CA gene using the Ruby Chip. PIK3CA is essential for regulating multiple cellular processes through the PI3K/AKT/mTOR signaling pathway including cell growth, proliferation, survival, and metabolism.

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Stilla® Ruby Chip

Catalog Number: (77392-266)
Supplier: STILLA TECHNOLOGIES, INC.
Description: The Ruby Chip features cutting-edge, patented microfluidic technology that integrates the entire digital PCR workflow into a single fully automation-compatible consumable.
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Crystal Digital PCR® Assay for NRAS (G12, G12D)

Supplier: STILLA TECHNOLOGIES, INC.
Description: Assay-specific Crystal Flex Probes and primers for the detection of NRAS mutations and its Positive Control. NRAS (G12, G12D) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 1 mutation in the NRAS gene using the Ruby Chip. NRAS is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma and colorectal cancer.

New Product

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Crystal Digital PCR® Assay for HPV (ALB, HPV16/18/31/33/35)

Supplier: STILLA TECHNOLOGIES, INC.
Description: Assay-specific Crystal Flex Probes and primers for the detection of HPV genotypes and its positive control. HPV (ALB, HPV16/18/31/33/35) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 5 high risk HPV genotypes for cervical cancer plus a reference gene for human DNA quantification using the Ruby Chip.

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Stilla® Nio™ Digital PCR Instrument

Supplier: STILLA TECHNOLOGIES, INC.
Description: The Nio™ digital PCR instrument line offers a simple all-in-one digital PCR workflow that supports seven colors, flexible throughput of up to 768 samples per day with three configurations, continuous loading, and easy-to-use software.

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Crystal Digital PCR® Assay for BRCA1/RAD51C/GSTP1 Methylation

Supplier: STILLA TECHNOLOGIES, INC.
Description: Assay-specific crystal flex probes and primers for the detection of BRCA1/RAD51C/GSTP1 methylation and its positive control. The BRCA1/RAD51C/GSTP1 methylation Crystal Digital PCR® assay is a 10X assay designed to detect and quantify methylation of the BRCA1, RAD51C, and GSTP1 promoter using the ruby chip. Methylation of the BRCA1, RAD51C, and GSTP1 affects DNA repair mechanisms crucial for genome stability and dysregulation of detoxification pathways, both contributing to tumor initiation, progression, and drug resistance.

New Product

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Crystal Digital PCR® Assay for TP53 (drop-off V272-A276/G280-R283)

Supplier: STILLA TECHNOLOGIES, INC.
Description: Assay-specific Crystal Flex Probes and primers for the detection of TP53 mutations and its Positive Control. TP53 (drop-off V272-A276/G280-R283) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify mutations between V272-A276 or G280-R283 of the TP53 gene using the Ruby Chip. TP53 is pivotal in regulating cell divisison, thus an important tumor suppressor gene.

New Product

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Crystal Digital PCR® Assay for NRAS (Q61, Q61R, Q61K)

Supplier: STILLA TECHNOLOGIES, INC.
Description: Assay-specific Crystal Flex Probes and primers for the detection of NRAS mutations and its Positive Control. NRAS (Q61, Q61R, Q61K) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 2 mutations in the NRAS gene using the Ruby Chip. NRAS is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma and colorectal cancer.

New Product

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Crystal Digital PCR® Assay for KRAS (G12A, G12C, G12D, G12V, drop-off G12-G13)

Supplier: STILLA TECHNOLOGIES, INC.
Description: Assay-specific crystal flex probes and primers for the detection of KRAS mutations and its positive control. The KRAS (G12A, G12C, G12D, G12V, drop-off G12-G13) Crystal Digital PCR® assay is a 10X assay designed to detect and quantify mutations in codons 12 and 13 plus 4 mutations in the KRAS gene using the ruby chip. KRAS is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma and colorectal cancer.

New Product

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Crystal Digital PCR® Assay for RAD51C Methylation

Supplier: STILLA TECHNOLOGIES, INC.
Description: Assay-specific crystal flex probes and primers for the detection of RAD51C Methylation and its positive control. The RAD51C methylation Crystal Digital PCR® assay is a 10X assay designed to detect and quantify methylation of the RAD51C promoter using the ruby chip. RAD51C gene is involved in DNA repair, particularly in the homologous recombination pathway for genome stability.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
In order to process your orders without delay, we request that you provide the required business documentation to purchase this product.

To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

  • State issued document with your organization's Federal Tax ID Number
  • State issued document with your organization's Resale Tax ID Number
  • City or County issued Business License
  • State Department of Health Services License
  • Any other ID issued by the State that includes the business name and address

* Please note if your account is within the State of California two of these pieces of identification will be required.
VWR will not lift restrictions for residential shipping addresses.

-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
This product has been blocked by your organization. Please contact your purchasing department for more information.
The original product is no longer available. The replacement shown is available.
This product is no longer available. Alternatives may be available by searching with the VWR Catalog Number listed above. If you need further assistance, please call VWR Customer Service at 1-800-932-5000.
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