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Catalog Number: (100246-010)
Supplier: Southern Biotechnology
Description: CD62E represents the 97 kDa type I transmembrane glycoprotein E-selectin, also known as endothelial-leukocyte adhesion molecule-1 (ELAM-1). It is expressed on cytokine-stimulated endothelium, weakly on unactivated endothelium, and is absent on leukocytes. Like other selectins, CD62E is an adhesion molecule that contributes to the initial attachment and rolling of leukocytes on endothelial surfaces, a prerequisite for leukocyte extravasation into tissues. CD62P is a 140 kDa membrane glycoprotein formerly known as platelet activation-dependent granule membrane protein (PADGEM) or GMP-140. It is expressed on platelets, megakaryocytes, and epithelium. It is thought to mediate the adhesive interactions of neutrophils and monocytes with endothelium in inflammatory responses and of activated platelets to neutrophils and monocytes in hemostasis. The monoclonal antibody 1.2B6 recognizes a common epitope shared by CD62E and CD62P.


Catalog Number: (103265-116)
Supplier: Southern Biotechnology
Description: Purified Donkey Anti-Goat IgG Fc antibody for use in ELISA assays.


Catalog Number: (100245-478)
Supplier: Southern Biotechnology
Description: Chicken CD45 is a transmembrane glycoprotein expressed on all leukocytes. B lineage cells in the bursa of Fabricius express the 215 kDa isoform while T lineage cells bear the 190 kDa variant. These high molecular weight molecules have intrinsic phosphotyrosine phosphatase activity characteristic of mammalian CD45. Levels of CD45 expression detected by the monoclonal antibody LT40 in the avian thymus are heterogeneous with approximately 90% of thymocytes expressing fourfold higher levels of surface CD45 (CD45hi) than do the remaining 10% (CD45low) of thymocytes. The CD45low population contains exclusively thymocytes with the CD3-CD4-CD8low phenotype characteristic of the immediate precursors to the CD3-CD4+CD8+ thymic population which are CD45hi. This shift from low to high levels of surface CD45 expression is concomitant with the transition from CD4-CD8low to CD4+CD8+ and before the expression of CD3. The ability of the monoclonal antibody LT40 to discriminate this CD45low subpopulation provides a suitable marker for the CD3-CD4-CD8low immediate precursors to the CD3-CD4+CD8+ thymocytes.


Catalog Number: (100245-554)
Supplier: Southern Biotechnology
Description: Like their mammalian counterparts, avian MHC Class I molecules, also known as B-F antigens, consist of a highly polymorphic α-chain noncovalently bound to the invariant β2-microglobulin subunit. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes which are usually cytotoxic T cells. The monoclonal antibody F21-21 also reacts with turkey β2-microglobulin.


Catalog Number: (100242-870)
Supplier: Southern Biotechnology
Description: FITC Anti-Mouse Lambda antibody for use in flow cytometry, immunohistochemistry, and western blotting assays.


Catalog Number: (100245-500)
Supplier: Southern Biotechnology
Description: The chicken Ia antigen is expressed on B cells, a subpopulation of the monocyte/macrophage lineage of cells, and mitogen-activated T cells. The molecule recognized by this antibody is similar in structure to the murine Ia antigens and human DR antigens.


Catalog Number: (103265-560)
Supplier: Southern Biotechnology
Description: FITC Anti-Mouse Foxp3 antibody for use in flow cytometry and immunohistochemistry assays.


Catalog Number: (100242-002)
Supplier: Southern Biotechnology
Description: Rat IgG-FITC for use as a control in flow cytometry and immunohistochemistry / immunocytochemistry assays.


Catalog Number: (100244-310)
Supplier: Southern Biotechnology
Description: Purified Goat Anti-Human IgA antibody for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, ELISpot, multiplex, purification, and depletion assays.


Catalog Number: (103265-720)
Supplier: Southern Biotechnology
Description: CD20 is a 33-37 kDa unglycosylated phosphoprotein. Although not a member of the tetraspanin superfamily of cell surface receptors, it crosses the cell membrane four times. It is expressed on all stages of B cell differentiation except plasma cells. The CD20 molecule is involved in regulation of B cell differentiation presumably via its reported function as a Ca++ channel subunit.


Catalog Number: (100245-124)
Supplier: Southern Biotechnology
Description: Rabbit Anti-Sheep IgG(H+L)-AP antibody for use in ELISA, immunohistochemistry / immunocytochemistry, and western blotting assays.


Catalog Number: (100245-762)
Supplier: Southern Biotechnology
Description: Biotin Anti-Human IgA1 antibody for use in ELISA, flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, ELISpot, separation, and multiplex assays.


Catalog Number: (103264-398)
Supplier: Southern Biotechnology
Description: Goat Anti-Mouse IgG Fc-Alexa Fluor 488 antibody for use in fluorescent assays including western blotting assays.


Catalog Number: (100245-634)
Supplier: Southern Biotechnology
Description: The monoclonal antibody KUL01 is useful in the study of the development, distribution, function, and ontogeny of the mononuclear phagocyte system (MPS) of the chicken by exclusively recognizing the cells of the MPS. It identifies chicken monocytes and macrophages as well as interdigitating cells and activated microglia cells. This antibody does not react with B (Bu-1+) or T (CD3+) lymphocytes.


Catalog Number: (100243-498)
Supplier: Southern Biotechnology
Description: CD154, formerly known as CD40 ligand and gp39, is a type II integral membrane protein and a member of the tumor necrosis factor (TNF) family of ligands. It is an important accessory molecule in T cell-B cell costimulatory interactions and is expressed predominantly on activated CD4+ T lymphocytes. It is also present on the surface of activated Th0, Th1, and Th2 T cell clones. Its expression is transient and cyclosporin-sensitive. The MR1 monoclonal antibody binds to murine CD154 with high affinity, blocks binding to CD40, and blocks CD154 function. Administration of this antibody to mice blocks the ability to mount primary and secondary immune responses to TD antigens yet does not alter the immune response to TI antigens.


Catalog Number: (100242-026)
Supplier: Southern Biotechnology
Description: Goat IgG-PE/CY5 (SPRD) for use as a control in flow cytometry assays.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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