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Description: SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA.SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA.

Catalog Number: 10099-796

Supplier: Prosci

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Description: Rabbit Polyclonal antibody to 14-3-3 theta (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide)

Catalog Number: 89320-880

Supplier: Genetex

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Catalog Number: EM8.22312.0250

Supplier: MilliporeSigma

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Description: Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway.Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Two transcript variants encoding different isoforms have been found for this gene.Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Two transcript variants encoding different isoforms have been found for this gene.

Catalog Number: 10109-534

Supplier: Prosci

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Description: This gene encodes a mitochondrion outer membrane protein that catalyzes the hydroxylation of L-tryptophan metabolite, L-kynurenine, to form L-3-hydroxykynurenine. Studies in yeast identified this gene as a therapeutic target for Huntington disease. [provided by RefSeq, Oct 2011]

Catalog Number: 77438-080

Supplier: Bioss

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Description: Anti-Tryptophan Hydroxylase/TPH Rabbit Monoclonal Antibody [clone: EP1311Y] (Alexa Fluor® 750)

Catalog Number: ABCA_AB321676-100U

Supplier: ABCAM INC.

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Description: It recognizes indoleamine 2, 3-dioxygenase1 is a 41-42 kD intracellular enzyme that catabolizes tryptophan into kynurenine. IDO1 modulates levels of the amino acid tryptophan, which is vital for cell growth, but is also involved in the suppression of the immune response.

Catalog Number: RL210301E58S

Supplier: Rockland Immunochemical

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Description: Sequence: Boc-Trp(Boc)-OH

Catalog Number: A-4550.0005BA

Supplier: Bachem Americas

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Description: Catalyzes the first and rate-limiting step in the kynurenine pathway of tryptophan catabolism.

Catalog Number: 76100-652

Supplier: Bioss

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Description: Application:8-Aminooctanoic Acid is a substance used in the study on the activity and specificity of ω-aminooctanoic acid-glycine-aspartic acid-tryptophan peptide in inhibiting platelet aggregation. Study on lysine analog effect on plasminogen binding in PC12 cells.

Catalog Number: ALA165345-5G

Supplier: ALADDIN SCIENTIFIC

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Description: Tryptophan hydroxylase (TPH) catalyzes the first step in the biosynthesis of serotonin and melatonin. In mammals, serotonin biosynthesis occurs predominantly in neurons which originate in the raphe nuclei of the brain, and melatonin synthesis takes place within the pineal gland. Although TPH catalyzes the same reaction within the raphe nuclei and the pineal gland, TPH activity is rate-limiting for serotonin but not melatonin biosynthesis..

Catalog Number: 10075-550

Supplier: Prosci

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Description: This diagnostic-grade product is an aqueous solution containing 20% human albumin (w/v). It is prepared by cold-alcohol fractionation from pooled human plasma obtained from venous blood. The USP Pharmacopeia requires that all fractionators add sodium caprylate and sodium tryptophanate as a preservative.

Catalog Number: 76994-318

Supplier: GeminiBio

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Description: Catalyzes the first and rate-limiting step in the kynurenine pathway of tryptophan catabolism.

Catalog Number: 76100-650

Supplier: Bioss

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Description: For use in determining phenylalaine deaminase, and tryptophan deaminase reactions.

Catalog Number: 89407-514

Supplier: Hardy Diagnostics

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Description: This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. The function of the protein has not been determined. Two alternatively spliced variants have been described.

Catalog Number: 76008-718

Supplier: Prosci

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Description: SG-Chymotrypsin™ is a serine endopeptidase, which predominantly cleaves peptide bonds on the carboxy side of tyrosine, phenylalanine and tryptophan

Catalog Number: 82022-518

Supplier: G-Biosciences

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