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Description: The Raf kinases are important intermediates in signal transduction. Raf protein family members, including A Raf and B Raf, have intrinsic serine/threonine kinase activity. Interaction between Ras proteins and Raf proteins results in Raf-mediated phosphorylation and activation of MEK (also known as MAP kinase kinase). Defects in BRAF are involved in a wide range of cancers. B-Raf is a serine/threonine protein kinase that acts as a signal transducer from membrane-associated receptors to nuclear transcription factors. 1 BRAF is important for the regulation of cell proliferation and determination of cell fate during embryogenesis. BRAF acts downstream of Ras and upstream of MEK in the Ras-Raf-MEK-ERK signal transduction pathway, which is a conserved RAS-activated protein kinase cascade that regulates cell growth, proliferation, and differentiation in response to growth factors, cytokines, and hormones.
Catalog Number: 10411-204
Supplier: Bioss


Description: The Raf kinases are important intermediates in signal transduction. Raf protein family members, including A Raf and B Raf, have intrinsic serine/threonine kinase activity. Interaction between Ras proteins and Raf proteins results in Raf-mediated phosphorylation and activation of MEK (also known as MAP kinase kinase). Defects in BRAF are involved in a wide range of cancers. B-Raf is a serine/threonine protein kinase that acts as a signal transducer from membrane-associated receptors to nuclear transcription factors. 1 BRAF is important for the regulation of cell proliferation and determination of cell fate during embryogenesis. BRAF acts downstream of Ras and upstream of MEK in the Ras-Raf-MEK-ERK signal transduction pathway, which is a conserved RAS-activated protein kinase cascade that regulates cell growth, proliferation, and differentiation in response to growth factors, cytokines, and hormones.
Catalog Number: 10411-206
Supplier: Bioss


Description: The Raf kinases are important intermediates in signal transduction. Raf protein family members, including A Raf and B Raf, have intrinsic serine/threonine kinase activity. Interaction between Ras proteins and Raf proteins results in Raf-mediated phosphorylation and activation of MEK (also known as MAP kinase kinase). Defects in BRAF are involved in a wide range of cancers. B-Raf is a serine/threonine protein kinase that acts as a signal transducer from membrane-associated receptors to nuclear transcription factors. 1 BRAF is important for the regulation of cell proliferation and determination of cell fate during embryogenesis. BRAF acts downstream of Ras and upstream of MEK in the Ras-Raf-MEK-ERK signal transduction pathway, which is a conserved RAS-activated protein kinase cascade that regulates cell growth, proliferation, and differentiation in response to growth factors, cytokines, and hormones.
Catalog Number: 10411-202
Supplier: Bioss


Description: The Raf kinases are important intermediates in signal transduction. Raf protein family members, including A Raf and B Raf, have intrinsic serine/threonine kinase activity. Interaction between Ras proteins and Raf proteins results in Raf-mediated phosphorylation and activation of MEK (also known as MAP kinase kinase). Defects in BRAF are involved in a wide range of cancers. B-Raf is a serine/threonine protein kinase that acts as a signal transducer from membrane-associated receptors to nuclear transcription factors. 1 BRAF is important for the regulation of cell proliferation and determination of cell fate during embryogenesis. BRAF acts downstream of Ras and upstream of MEK in the Ras-Raf-MEK-ERK signal transduction pathway, which is a conserved RAS-activated protein kinase cascade that regulates cell growth, proliferation, and differentiation in response to growth factors, cytokines, and hormones.
Catalog Number: 10411-208
Supplier: Bioss


Description: Assay-specific Crystal Flex Probes and primers for the detection of BRAF mutations and its Positive Control. BRAF (V600E, drop-off V600) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify mutations in codons V600-K601 plus 1 mutation in the BRAF gene. BRAF is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma, colorectal cancer and thyroid cancer, through its role in the MAPK/ERK pathway. Mutations in BRAF, particularly the V600E mutation, lead to uncontrolled cell proliferation and survival.
Catalog Number: 77590-138
Supplier: STILLA TECHNOLOGIES, INC.

New Product


Description: The B-Raf Antibody (5A9) from Novus Biologicals is a mouse monoclonal antibody to B-Raf. This antibody reacts with human, monkey. The B-Raf Antibody (5A9) has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.
Catalog Number: 102177-570
Supplier: Novus Biologicals


Description: The B-Raf Antibody (1H12) from Novus Biologicals is a mouse monoclonal antibody to B-Raf. This antibody reacts with human, mouse. The B-Raf Antibody (1H12) has been validated for the following applications: Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.
Catalog Number: 102177-218
Supplier: Novus Biologicals


Description: Rabbit monoclonal [ARC1587] antibody to BRAF (phospho Thr401) for WB with samples derived from Human, Mouse and Rat.
Catalog Number: 77230-580
Supplier: ANTIBODIES.COM LLC


Description: Mouse monoclonal [V600E/1321] antibody to BRAF (mutated V600E) for ELISA with samples derived from Human.
Catalog Number: 77175-958
Supplier: ANTIBODIES.COM LLC


Description: Mouse monoclonal [V600E/1322] antibody to BRAF (mutated V600E) for ELISA with samples derived from Human.
Catalog Number: 77175-956
Supplier: ANTIBODIES.COM LLC


Description: Mouse monoclonal [V600E/1322] antibody to BRAF (mutated V600E) for ELISA with samples derived from Human.
Catalog Number: 77178-724
Supplier: ANTIBODIES.COM LLC


Description: Mouse monoclonal [V600E/1321] antibody to BRAF (mutated V600E) for ELISA with samples derived from Human.
Catalog Number: 77178-726
Supplier: ANTIBODIES.COM LLC


Description: Human B-Raf Proto Oncogene Serine/Threonine Protein Kinase (BRAF) ELISA Kit
Catalog Number: 77538-034
Supplier: Bioss


Description: Human BRAF (B-Raf Proto Oncogene Serine/Threonine Protein Kinase) ELISA Kit
Catalog Number: 77518-298
Supplier: AFG BIOSCIENCE LLC


Description: 30514
Catalog Number: 77808-178
Supplier: AFG BIOSCIENCE LLC

New Product


Description: 30515
Catalog Number: 77808-179
Supplier: AFG BIOSCIENCE LLC

New Product


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