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4-fluoro ADB (CRM), Cayman Chemical

Description: A Certified Reference Material
Catalog Number: 76544-130
Supplier: Cayman Chemical Company
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Mirtazapine-d3 (CRM), Cayman Chemical

Description: A Certified Reference Material
Catalog Number: 76544-556
Supplier: Cayman Chemical Company
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Morphine-d3 (CRM), Cayman Chemical

Description: A Certified Reference Material
Catalog Number: 76544-342
Supplier: Cayman Chemical Company
Image Unavailable-76544-312

(±)-Amphetamine-d11 (hydrochloride) (CRM), Cayman Chemical

Description: A Certified Reference Material
Catalog Number: 76544-312
Supplier: Cayman Chemical Company
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Clonazolam (CRM), Cayman Chemical

Description: A Certified Reference Material
Catalog Number: 76544-372
Supplier: Cayman Chemical Company
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Pentobarbital (CRM), Cayman Chemical

Description: A Certified Reference Material
Catalog Number: 76544-230
Supplier: Cayman Chemical Company
Image Unavailable-76544-212

3,4-MDMA-d5 (hydrochloride) (CRM), Cayman Chemical

Description: A Certified Reference Material
Catalog Number: 76544-212
Supplier: Cayman Chemical Company
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Methylone (hydrochloride) (CRM), Cayman Chemical

Description: A Certified Reference Material
Catalog Number: 76544-224
Supplier: Cayman Chemical Company
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Ocfentanil (hydrochloride) (CRM), Cayman Chemical

Description: A Certified Reference Material
Catalog Number: 76544-112
Supplier: Cayman Chemical Company
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Norketamine (hydrochloride) (CRM), Cayman Chemical

Description: A Certified Reference Material
Catalog Number: 76544-168
Supplier: Cayman Chemical Company
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Butyryl fentanyl-d5 (hydrochloride) (CRM), Cayman Chemical

Description: A Certified Reference Material
Catalog Number: 76544-084
Supplier: Cayman Chemical Company
Image Unavailable-76543-974

AB-PINACA N-pentanoic acid metabolite-d4 (CRM), Cayman Chemical

Description: An internal standard for the quantification of AB-PINACA N-pentanoic acid metabolite by GC- or LC-MS
Catalog Number: 76543-974
Supplier: Cayman Chemical Company
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α-methyl Acetyl fentanyl (hydrochloride) (CRM), Cayman Chemical

Description: A Certified Reference Material
Catalog Number: 76544-442
Supplier: Cayman Chemical Company
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Phentermine-d5 (hydrochloride) (CRM), Cayman Chemical

Description: A Certified Reference Material
Catalog Number: 76544-726
Supplier: Cayman Chemical Company
Image Unavailable-76544-740

AB-PINACA (CRM), Cayman Chemical

Description: A Certified Reference Material
Catalog Number: 76544-740
Supplier: Cayman Chemical Company
Image Unavailable-76292-928

ML RR-S2 CDA (ammonium salt) ≥98%

Description: ML RR-S2 CDA is a synthetic cyclic dinucleotide (CDN) that contains non-canonical 2'5'-phosphodiester bonds and is an activator of stimulator of interferon genes (STING).1 It contains mixed linkages (ML) with both 2'5' and 3'5' linkages, which leads to increased thermal stability of human STING in a differential scanning fluorimetry (DSF) assay. ML RR-S2 CDA increases type I interferon production by THP-1 human monocytes relative to unmodified cyclic di-AMP (CDA; Item No. 17753), indicating the ML enhances its action at human STING. It induces expression of IFN-β and the pro-inflammatory cytokines TNF-α, IL-6, and Mcp-1 in murine bone marrow macrophages (BMM) isolated from wild-type, but not STING-/-, mice. ML RR-S2 CDA also induces IFN-β expression in peripheral blood mononuclear cells (PBMCs) isolated from donors carrying STINGWT/WT, STINGWT/REF, and STINGWT/HAQ alleles. In vivo, ML RR-S2 CDA initiates tumor regression and prevents tumor growth upon tumor cell reimplantation in 4T1 breast and CT26 colon cancer mouse xenograft models.
Catalog Number: 76292-928
Supplier: Cayman Chemical Company
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