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Supplier: PeproTech, Inc.

Description: TIGAR is a p53-inducible enzyme that catalyzes the hydrolysis of fructose-2-6 bisphosphate (F-2-6-BP) to fructose-6-phosphate and inorganic phosphate. F-2-6-BP is a powerful activator of 6-phosphofructose-1 kinase, the rate limiting enzyme of glycolysis. By lowering the intracellular level of F-2-6-BP, TIGAR expression leads to increased glucose processing via the pentose phosphate pathway, the major cellular source for NADPH. Recombinant Human TIGAR expressed in

Supplier: PeproTech, Inc.

Description: LAG-1 is CC chemokine that signals through the CCR5 receptor. LAG-1 is identical to MIP-1β (ACT II isotype) except for two amino acid substitutions; arginine for histidine at position 22 and serine for glycine at position 47 of the mature protein. LAG-1 chemoattracts monocytes, and exhibits activity as an HIV-suppressive factor. Recombinant Human LAG-1 (CCL4L1) is a 7.7 kDa protein containing 69 amino acid residues.

Supplier: PeproTech, Inc.

Description: The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF1 is essential for normal differentiation of the antral and pyloric gastric mucosa, and functions as a gastric-specific tumor suppressor gene. Recombinant Human TFF-1 is a 6.7 kDa monomeric protein consisting of a 60 amino acid polypeptide chain, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds.

Supplier: PeproTech, Inc.

Description: The MCP proteins are members of the CC chemokine family that signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross-reacts across species. Recombinant Human MCP-4 (CCL13) is an 8.6 kDa protein containing 75 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

Catalog Number: (10774-876)

Supplier: PeproTech, Inc.

Description: Monoclonal AntibodyProduced in BALB/c x ICR F1-mice immunized with highly pure Recombinant Human LEC (CCL16). Anti­Human LEC (CCL16)­specific antibody was purified from ascites fluid by Protein G affinity chromatography.

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Catalog Number: (10774-878)

Supplier: PeproTech, Inc.

Description: Monoclonal AntibodyProduced in BALB/c x ICR F1-mice immunized with highly pure Recombinant Human SCF. Anti­Human SCF­specific antibody was purified from ascites fluid by Protein A affinity chromatography.

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Supplier: PeproTech, Inc.

Description: 4-1BB receptor, a member of the TNFR superfamily of receptors, is mainly expressed on the surface of T cells, but also found in B cells, monocytes, and various transformed cell lines. 4-1BB receptor binds to 4-1BBL to provide a co-stimulatory signal for T lymphocytes. Signaling by 4-1BB receptor has been implicated in the antigen-presentation process and generation of cytotoxic T cells. The human 4-1BB receptor gene codes for a 255 amino acid type I transmembrane protein containing a 17 amino acid N-terminal signal sequence, a 169 amino acid extracellular domain, a 27 amino acid transmembrane domain and a 42 amino acid cytoplasmic domain. Recombinant Human 4-1BB Receptor is a 167 amino acid polypeptide (17.7 kDa), which contains the cysteine-rich TNFR-like extracellular domain of 4-1BB receptor.

Supplier: PeproTech, Inc.

Description: Produced from sera of rabbits immunized with highly pure Recombinant Human IL-8 (CXCL8). Anti­Human IL-8 (CXCL8)­specific antibody was purified by affinity chromatography and then biotinylated.

Supplier: PeproTech, Inc.

Description: Human ONCOSTATIN M, Polyclonal Antibody, Source: Rabbit, Preparation: purified by affinity chromatography employing immobilized hOncostatin M matrix, Immunogen:E.coli derived Recombinant Human Oncostatin M (227 a.a.), Application:ELISA, Western Blot, Neutralization, 50ug

Catalog Number: (10775-028)

Supplier: PeproTech, Inc.

Description: Produced from sera of rabbits immunized with highly pure Recombinant Human IGF-II. Anti­Human IGF-II­specific antibody was purified by affinity chromatography and then biotinylated.

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Catalog Number: (10775-030)

Supplier: PeproTech, Inc.

Description: Human IGF-II, Animal Free, Polyclonal Antibody, Source: Rabbit, Preparation: purified by affinity chromatography and then biotinylated, Immunogen:E.coli derived Recombinant Human IGF-II, Application:ELISA, Western Blot, 50ug

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Supplier: PeproTech, Inc.

Description: Produced from sera of rabbits immunized with highly pure Recombinant Human Flt3-Ligand. Anti­Human Flt3-Ligand­specific antibody was purified by affinity chromatography and then biotinylated.

Supplier: PeproTech, Inc.

Description: Animal-Free Murine IL-22 Recombinant Protein, Purity: >98%, Source: E.coli, Biological Activity: By its ability to induce IL-10 secretion in COLO 205 (human colon carcinoma cells), Synonyms: Interleukin-

Supplier: PeproTech, Inc.

Description: The Insulin/Relaxin structural family of proteins consists of at least seven members, each containing an insulin-like heterodimeric structure of two polypeptide chains held together by two inter-chain disulfide bonds. The INSL5/INSL7 hybrid contains the β-chain of INSL7 (Relaxin-3), linked to the α-chain of INSL5. The INSL5/INSL7 hybrid protein can specifically activate the G protein-coupled receptors, GPCR135 and GPCR142, but unlike Relaxin-3, does not induce significant activation of the LGR7 receptor. Recombinant Human INSL5/INSL7 Hybrid is a heterodimeric, 5.2 kDa protein consisting of a 27 amino acid β-chain linked to a 21 amino acid α-chain by two disulfide bonds.

Supplier: PeproTech, Inc.

Description: Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life.  BMP-10 plays a crucial role in the development of the embryonic heart by acting to stimulate and maintain cardiomyocyte proliferation.  It can signal through various receptor complexes usually containing BMPR-1A, BMPR-1B, ALK1, ALK3, or ALK6. The interaction of BMP-10 with its specific receptors can induce signaling initiated by the phosphorylation of SMAD transcription factors, including SMAD1, SMAD5, or SMAD8, but can also induce SMAD independent processes.  BMP-10 is structurally related to BMP-9, and both can inhibit endothelial cell proliferation and migration. Recombinant Human BMP-10 is a 24.4 kDa homodimeric disulfide-linked protein consisting of two 108 amino acid subunits, which correspond to amino acid residues 317 to 424 of the full-length BMP-10 precursor.

Supplier: PeproTech, Inc.

Description: TGF-β family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth, and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling, and maintenance of a variety of other tissues and organs. BMP-5 is expressed in the nervous system, lungs and liver. It is a known regulator for dendritic growth in sympathetic neurons. BMP-5 is a 454 amino acid precursor protein that is cleaved to release the biologically active C-terminal mature protein. Recombinant Human BMP-5 is a 31.2 kDa homodimeric disulfide-linked protein consisting of two identical 138 amino acid chains.