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Supplier: PeproTech, Inc.

Description: Produced from sera of rabbits immunized with highly pure Recombinant Human Fractalkine (CX3CL1). Anti­Human Fractalkine (CX3CL1)­specific antibody was purified by affinity chromatography and then biotinylated.

Supplier: PeproTech, Inc.

Description: The three mammalian isoforms of TGF-β, TGF-β1, β2, and β3, signal through the same receptor and elicit similar biological responses. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation and motility, as well as synthesis and deposition of the extracellular matrix. They are involved in various physiological processes, including embryogenesis, tissue remodeling and wound healing. They are secreted predominantly as latent complexes, which are stored at the cell surface and in the extracellular matrix. The release of the biologically active TGF-β isoform from a latent complex involves proteolytic processing of the complex and /or induction of conformational changes by proteins such as thrombospondin-1. TGF-β2 has been shown to exert suppressive effects on IL-2-dependent T-cell growth, and may also have an autocrine function in enhancing tumor growth by suppressing immuno-surveillance of tumor development. Recombinant Human TGF-β2 is a 25.0 kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond.

Supplier: PeproTech, Inc.

Description: Produced from sera of rabbits immunized with highly pure Recombinant Human NNT-1/BCSF-3. Anti­Human NNT-1/BCSF-3­specific antibody was purified by affinity chromatography employing an immobilized Human NNT-1/BCSF-3 matrix.

Catalog Number: (10781-660)

Supplier: PeproTech, Inc.

Description: PeproTech's Human/Murine/Rat BMP-2 ELISA development kit contains the key components required for the quantitative measurement of natural and/or recombinant human/murine/rat BMP-2 in a sandwich ELISA format.

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Supplier: PeproTech, Inc.

Description: Produced from sera of rabbits immunized with highly pure Recombinant Rat IL-7. Anti­Rat IL-7­specific antibody was purified by affinity chromatography employing an immobilized Rat IL-7 matrix.

Supplier: PeproTech, Inc.

Description: Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The four known members of this family, resistin, RELMα, RELMβ, and RELMγ, share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that resistin expression is severely suppressed in obesity, and that it may act as a feedback regulator of Adipogenesis. Recombinant Rat Resistin is a 20.0 kDa, disulfide-linked, homodimeric protein composed of two 94 identical amino acid chains linked by a single disulfide bond.

Supplier: PeproTech, Inc.

Description: Produced from sera of rabbits immunized with highly pure Recombinant Human IL-1RA. Anti­Human IL-1RA­specific antibody was purified by affinity chromatography employing an immobilized Human IL-1RA matrix.

Catalog Number: (10774-888)

Supplier: PeproTech, Inc.

Description: Monoclonal AntibodyProduced in BALB/c-mice immunized with highly pure Recombinant Human IP-10 (CXCL10). Anti­Human IP-10 (CXCL10)­specific antibody was purified from cell culture by Protein A affinity chromatography.

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Catalog Number: (10771-552)

Supplier: PeproTech, Inc.

Description: PeproTech's Murine G-CSF ELISA development kit contains the key components required for the quantitative measurement of natural and/or recombinant murine G-CSF in a sandwich ELISA format.

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Catalog Number: (10771-536)

Supplier: PeproTech, Inc.

Description: PeproTech's Human MIG (CXCL9) ELISA development kit contains the key components required for the quantitative measurement of natural and/or recombinant human MIG (CXCL9) in a sandwich ELISA format.

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Supplier: PeproTech, Inc.

Description: TGF-β family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth, and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling, and maintenance of a variety of other tissues and organs. BMP-5 is expressed in the nervous system, lungs and liver. It is a known regulator for dendritic growth in sympathetic neurons. BMP-5 is a 454 amino acid precursor protein that is cleaved to release the biologically active C-terminal mature protein. Recombinant Human BMP-5 is a 31.2 kDa homodimeric disulfide-linked protein consisting of two identical 138 amino acid chains.

Catalog Number: (10774-836)

Supplier: PeproTech, Inc.

Description: Monoclonal AntibodyProduced in BALB/c x ICR F1-mice immunized with highly pure Recombinant Human IL-4. Anti­Human IL-4­specific antibody was purified from ascites fluid by Protein A affinity chromatography.

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Supplier: PeproTech, Inc.

Description: BAFF, a member of the TNF superfamily of ligands, is expressed in T cells, macrophages, monocytes and dendritic cells. BAFF is involved in stimulation of B and T cell function, and is an important survival and maturation factor for peripheral B cells. BAFF signals through three different TNF receptors, TACI, BCMA and BAFF-R. The human BAFF gene codes for a 285 amino acid type II transmembrane protein containing a 46 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 218 amino acid extracellular domain. Recombinant Human BAFF is a 152 amino acid polypeptide (17.0 kDa), which contains the TNF-like portion of the extracellular domain of BAFF.

Supplier: PeproTech, Inc.

Description: Produced from sera of rabbits immunized with highly pure Recombinant Human MCP-4 (CCL13). Anti­Human MCP-4 (CCL13)­specific antibody was purified by affinity chromatography employing an immobilized Human MCP-4 matrix.

Supplier: PeproTech, Inc.

Description: Produced from sera of goats immunized with highly pure Recombinant Human IL-12. Anti­Human IL-12­specific antibody was purified by affinity chromatography and then biotinylated.

Supplier: PeproTech, Inc.

Description: Interleukin-1 receptor antagonist (IL-1RA) is a naturally-occurring, inflammatory-inhibitor protein. It inhibits the activity of IL-1α and IL-1β by competitively blocking their binding to type I and type II receptors. IL-1RA is produced by corneal epithelial cells, monocytes, neutrophils, macrophages, and fibroblasts. Therapeutically, IL-1RA may help in the treatment of sepsis, cachexia, rheumatoid arthritis, chronic myelogenous leukemia, asthma, psoriasis, and inflammatory bowel disease. Recombinant Human IL-1RA is a 17.2 kDa protein consisting of 153 amino acid residues.