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Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00014223
Catalog Number: (10481-414)
Supplier: Bioss
Description: Peroxiredoxin (Prx) is an antioxidant enzyme detoxifying reactive oxygen species and has a cysteine at the active site. Prx enzymes modulate various receptor signaling pathways and protect cells from oxidatively induced death. Peroxiredoxin 1 to 4 have two conserved Cys residues corresponding to Cys51 and Cys172 of mammalian Peroxiredoxin 1. The active site cysteine(Cys51) is oxidized to cysteine sulfenic acid(Cys51-SOH) when a peroxide is reduced. Because Cys51-SOH is unstable, it forms a disulfide with Cys172-SH which comes from the other subunit of the homodimer. The disulfide is then reduced back to the Prx active thiol form by the thioredoxin-thioredoxin reductase system. However, the formation of the disulfide is a slow process. Thus under oxidative stress conditions, the sulfenic intermediate(Cys51-SOH) can be easily over oxidized to cysteine sulfinic acid(Cys-SO2H) or cysteine sulfonic acid(Cys-SO3H) before it is able to form a disulfide. Recent studies suggest that over oxidized Prx can be reduced back to the active form during recovery after oxidative stress.


Catalog Number: (10481-398)
Supplier: Bioss
Description: Peroxiredoxin (Prx) is an antioxidant enzyme detoxifying reactive oxygen species and has a cysteine at the active site. Prx enzymes modulate various receptor signaling pathways and protect cells from oxidatively induced death. Peroxiredoxin 1 to 4 have two conserved Cys residues corresponding to Cys51 and Cys172 of mammalian Peroxiredoxin 1. The active site cysteine(Cys51) is oxidized to cysteine sulfenic acid(Cys51-SOH) when a peroxide is reduced. Because Cys51-SOH is unstable, it forms a disulfide with Cys172-SH which comes from the other subunit of the homodimer. The disulfide is then reduced back to the Prx active thiol form by the thioredoxin-thioredoxin reductase system. However, the formation of the disulfide is a slow process. Thus under oxidative stress conditions, the sulfenic intermediate(Cys51-SOH) can be easily over oxidized to cysteine sulfinic acid(Cys-SO2H) or cysteine sulfonic acid(Cys-SO3H) before it is able to form a disulfide. Recent studies suggest that over oxidized Prx can be reduced back to the active form during recovery after oxidative stress.


Catalog Number: (AA40572-NC)
Supplier: Thermo Scientific Chemicals
Description: 50% w/w in Aqueous Solution, Reagent Grade,UN3211,Liquid,DANGER: OXIDIZER, burns skin and eyes,(c)2g,(c)10g,OXIDIZER,

Catalog Number: (77692-929)
Supplier: LGC STANDARDS
Description: (14bRS)-2-Methyl-1,2,3,4,10-14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepine 2-Oxide, Mikromol, LGC Standards

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Catalog Number: (77692-632)
Supplier: LGC STANDARDS
Description: Benperidol N-Oxide (cis and trans), Mikromol, LGC Standards

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Catalog Number: (89138-166)
Supplier: Biotium
Description: is a selective inhibitor for the brain nitric oxide synthase (NOS).


Supplier: ALKALI SCIENTIFIC MS
Description: Water Ultra Pure, CellPro™, Molecular Biology Grade Ultra Pure

Supplier: TLC PHARMACEUTICAL STANDARD LTD
Description: Pharmaceutical Standards, Ketotifen EP Impurity D (Ketotifen N-Oxide)

Catalog Number: (76706-070)
Supplier: AFG BIOSCIENCE LLC
Description: Mouse neuronal Nitric Oxide Synthase(nNOS) ELISA Kit


Catalog Number: (76710-170)
Supplier: AFG BIOSCIENCE LLC
Description: Rat Endothelial Nitric Oxide Synthase 3 (eNOS-3) ELISA Kit


Catalog Number: (76715-442)
Supplier: AFG BIOSCIENCE LLC
Description: Human Neuronal Nitric Oxide Synthase (nNOS) ELISA Kit


Supplier: Thermo Scientific Chemicals
Description: Silicon(IV) oxide is used in the manufacture of glass for windows, drinking glasses, beverage bottles and many other materials. Optical fibers for telecommunication are made from silica. It is also used as a raw material for many ceramics such as earthenware, stoneware and porcelain. In addition, silica is a common additive in the production of foods and pharmaceutical products.
Supplier: MilliporeSigma
Description: Meets Reagent Specifications for testing USP/NF monographs.
Supplier: Thermo Scientific Chemicals
Description: As a chemical intermediate
Supplier: Adipogen
Description: Potent and highly selective, irreversible inhibitor of soluble guanylyl cyclase (sGC). The binding is competitive with nitric oxide (NO). Tool to elucidate the nitric oxide (NO)-cGMP pathway. Apoptosis inhibitor Inhibits growth and migration of prostate cancer cells independent of its effects on GMP levels.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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